Speed congenics

Enquiries

 +612 6125 7757

Congenic strains are produced by transferring the transgene/KO allele to a new genetic background strain that is more appropriate for phenotypic analysis. Utilising the traditional, random backcrossing methods it can take over 3 years to produce a congenic strain containing 99% of the recipient genome.

The APF speed congenic service:

  • Utilises marker-assisted accelerated backcrossing as a congenic breeding strategy.
  • Uses a genome scanning set of approximately 100 single nucleotide (SNP)-based markers
  • Evaluates strain-specific polymorphisms at each backcross generation
  • Preselects the founders of each generation to bias for a new genetic background
  • Establishes a congenic strain within 18 months.

How to order

To initiate a project please provide details to the contact.

Updated:  27 March 2017/Responsible Officer:  Director/Page Contact:  Site manager